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Generation of mouse conditional knockout alleles in one step using the i-GONAD method
The Cre/loxP system is a powerful tool for gene function study in vivo. Regulated expression of Cre recombinase mediates precise deletion of genetic elements in a spatially– and temporally–controlled manner. Despite the robustness of this system, it requires a great amount of effort to create a cond...
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| Publicado no: | Genome Res |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7849380/ https://ncbi.nlm.nih.gov/pubmed/33328166 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.265439.120 |
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