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Generation of mouse conditional knockout alleles in one step using the i-GONAD method

The Cre/loxP system is a powerful tool for gene function study in vivo. Regulated expression of Cre recombinase mediates precise deletion of genetic elements in a spatially– and temporally–controlled manner. Despite the robustness of this system, it requires a great amount of effort to create a cond...

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Bibliografiske detaljer
Udgivet i:Genome Res
Main Authors: Shang, Renjie, Zhang, Haifeng, Bi, Pengpeng
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7849380/
https://ncbi.nlm.nih.gov/pubmed/33328166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.265439.120
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