ATP Citrate Lyase Mediates Resistance of Colorectal Cancer Cells to SN38

Combination chemotherapy is standard for metastatic colorectal cancer (CRC); however, nearly all patients develop drug resistance. Understanding the mechanisms that lead to resistance to individual chemotherapeutic agents may enable identification of novel targets and more effective therapy. Irinote...

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Publicado en:Mol Cancer Ther
Autores principales: Zhou, Yunfei, Bollu, Lakshmi Reddy, Tozzi, Federico, Ye, Xiangcang, Bhattacharya, Rajat, Gao, Guang, Dupre, Elizabeth, Xia, Ling, Lu, Jia, Fan, Fan, Bellister, Seth, Ellis, Lee M, Weihua, Zhang
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4302275/
https://ncbi.nlm.nih.gov/pubmed/24132143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-13-0098
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