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Equilibrium Kinetic Network of the Villin Headpiece in Implicit Solvent

We applied the single-replica multiple-state transition-interface sampling method to elucidate the equilibrium kinetic network of the 35-residue-fragment (HP-35) villin headpiece in implicit water at room temperature. Starting from the native Protein Data Bank structure, nine (meta)stable states of...

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Bibliografiske detaljer
Udgivet i:Biophys J
Main Authors: Du, Weina, Bolhuis, Peter G.
Format: Artigo
Sprog:Inglês
Udgivet: The Biophysical Society 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4302211/
https://ncbi.nlm.nih.gov/pubmed/25606685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.11.3476
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