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Effect of Thanatophoric Dysplasia Type I Mutations on FGFR3 Dimerization
Thanatophoric dysplasia type I (TDI) is a lethal human skeletal growth disorder with a prevalence of 1 in 20,000 to 1 in 50,000 births. TDI is known to arise because of five different mutations, all involving the substitution of an amino acid with a cysteine in fibroblast growth factor receptor 3 (F...
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| Publicat a: | Biophys J |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Biophysical Society
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4302202/ https://ncbi.nlm.nih.gov/pubmed/25606676 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.11.3460 |
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