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Strong dimerization of wild-type ErbB2/Neu transmembrane domain and the oncogenic Val664Glu mutant in mammalian plasma membranes

Here, we study the homodimerization of the transmembrane domain of Neu, as well as an oncogenic mutant (V664E), in vesicles derived from the plasma membrane of mammalian cells. For the characterization, we use a Förster resonance energy transfer (FRET)-based method termed Quantitative Imaging-FRET (...

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Bibliografske podrobnosti
Main Authors: Placone, Jesse, He, Lijuan, Del Piccolo, Nuala, Hristova, Kalina
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4082748/
https://ncbi.nlm.nih.gov/pubmed/24631664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2014.03.001
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