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Characterization of the Kinetics of Cardiac Cytosolic Malate Dehydrogenase and Comparative Analysis of Cytosolic and Mitochondrial Isoforms

Because the mitochondrial inner membrane is impermeable to pyridine nucleotides, transport of reducing equivalents between the mitochondrial matrix and the cytoplasm relies on shuttle mechanisms, including the malate-aspartate shuttle and the glycerol-3-phosphate shuttle. These shuttles are needed f...

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Bibliographic Details
Published in:Biophys J
Main Authors: Dasika, Santosh K., Vinnakota, Kalyan C., Beard, Daniel A.
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4302200/
https://ncbi.nlm.nih.gov/pubmed/25606689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.11.3466
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