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Phosphorylation in the Catalytic Cleft Stabilizes and Attracts Domains of a Phosphohexomutase

Phosphorylation can modulate the activities of enzymes. The phosphoryl donor in the catalytic cleft of α-D-phosphohexomutases is transiently dephosphorylated while the reaction intermediate completes a 180° reorientation within the cleft. The phosphorylated form of 52 kDa bacterial phosphomannomutas...

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Bibliografski detalji
Izdano u:Biophys J
Glavni autori: Xu, Jia, Lee, Yingying, Beamer, Lesa J., Van Doren, Steven R.
Format: Artigo
Jezik:Inglês
Izdano: The Biophysical Society 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4302199/
https://ncbi.nlm.nih.gov/pubmed/25606681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.12.003
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