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Phosphorylation in the Catalytic Cleft Stabilizes and Attracts Domains of a Phosphohexomutase
Phosphorylation can modulate the activities of enzymes. The phosphoryl donor in the catalytic cleft of α-D-phosphohexomutases is transiently dephosphorylated while the reaction intermediate completes a 180° reorientation within the cleft. The phosphorylated form of 52 kDa bacterial phosphomannomutas...
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| Publicado no: | Biophys J |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4302199/ https://ncbi.nlm.nih.gov/pubmed/25606681 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.12.003 |
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