Molecular Biophysics of Orai Store-Operated Ca(2+) Channels

Upon endoplasmic reticulum Ca(2+) store depletion, Orai channels in the plasma membrane are activated directly by endoplasmic reticulum-resident STIM proteins to generate the Ca(2+)-selective, Ca(2+) release-activated Ca(2+) (CRAC) current. After the molecular identification of Orai, a plethora of f...

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Bibliografiske detaljer
Udgivet i:Biophys J
Main Authors: Amcheslavsky, Anna, Wood, Mona L., Yeromin, Andriy V., Parker, Ian, Freites, J. Alfredo, Tobias, Douglas J., Cahalan, Michael D.
Format: Artigo
Sprog:Inglês
Udgivet: The Biophysical Society 2015
Fag:
Biophysical Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4302196/
https://ncbi.nlm.nih.gov/pubmed/25606672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.11.3473
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