Fixed dose artesunate amodiaquine – a phase IIb, randomized comparative trial with non-fixed artesunate amodiaquine

BACKGROUND: Pharmacokinetic (PK) and pharmacodynamic (PD) data are limited for artesunate (AS) and amodiaquine (AQ) in uncomplicated Plasmodium falciparum. METHODS: From 2007-8, 54 P. falciparum-infected, Kenyan adults were assigned randomly fixed dose (FD) ASAQ (n = 26) or non-fixed (NF) ASAQ (n = ...

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Detalles Bibliográficos
Publicado en:Malar J
Main Authors: Ogutu, Bernhards, Juma, Elizabeth, Obonyo, Charles, Jullien, Vincent, Carn, Gwenaelle, Vaillant, Michel, Taylor, Walter Robert John, Kiechel, Jean-René
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2014
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4302156/
https://ncbi.nlm.nih.gov/pubmed/25515698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-13-498
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