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Phosphorylation of Dok1 by Abl family kinases inhibits CrkI transforming activity
The Crk SH2/SH3 adaptor and the Abl nonreceptor tyrosine kinase were first identified as oncoproteins, and both can induce tumorigenesis when overexpressed or mutationally activated. We previously reported the surprising finding that inhibition or knockdown of Abl family kinases enhanced transformat...
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| Gepubliceerd in: | Oncogene |
|---|---|
| Hoofdauteurs: | , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2014
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4302068/ https://ncbi.nlm.nih.gov/pubmed/25043303 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.210 |
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