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Design, synthesis, and biological evaluation of aminothiazole derivatives against the fungal pathogens Histoplasma capsulatum and Cryptococcus neoformans

Invasive fungal disease constitutes a growing health burden and development of novel antifungal drugs with high potency and selectivity against new fungal molecular targets are urgently needed. Previously, an aminothiazole derivative, designated as 41F5, was identified in our laboratories as highly...

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Bibliografiska uppgifter
I publikationen:Bioorg Med Chem
Huvudupphovsmän: Khalil, Ahmed, Edwards, Jessica A., Rappleye, Chad A., Tjarks, Werner
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4302056/
https://ncbi.nlm.nih.gov/pubmed/25543205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2014.12.006
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