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Identification of an Aminothiazole with Antifungal Activity against Intracellular Histoplasma capsulatum
As eukaryotes, fungi possess relatively few molecules sufficiently unique from mammalian cell components to be used as drug targets. Consequently, most current antifungals have significant host cell toxicity. Primary fungal pathogens (e.g., Histoplasma) are of particular concern, as few antifungals...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3754333/ https://ncbi.nlm.nih.gov/pubmed/23817367 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00459-13 |
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