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Identification of an Aminothiazole with Antifungal Activity against Intracellular Histoplasma capsulatum

As eukaryotes, fungi possess relatively few molecules sufficiently unique from mammalian cell components to be used as drug targets. Consequently, most current antifungals have significant host cell toxicity. Primary fungal pathogens (e.g., Histoplasma) are of particular concern, as few antifungals...

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Bibliografski detalji
Glavni autori: Edwards, Jessica A., Kemski, Megan M., Rappleye, Chad A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754333/
https://ncbi.nlm.nih.gov/pubmed/23817367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00459-13
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