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Design, synthesis, and biological evaluation of aminothiazole derivatives against the fungal pathogens Histoplasma capsulatum and Cryptococcus neoformans

Invasive fungal disease constitutes a growing health burden and development of novel antifungal drugs with high potency and selectivity against new fungal molecular targets are urgently needed. Previously, an aminothiazole derivative, designated as 41F5, was identified in our laboratories as highly...

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Bibliografski detalji
Izdano u:Bioorg Med Chem
Glavni autori: Khalil, Ahmed, Edwards, Jessica A., Rappleye, Chad A., Tjarks, Werner
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4302056/
https://ncbi.nlm.nih.gov/pubmed/25543205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2014.12.006
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