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Design, synthesis, and biological evaluation of aminothiazole derivatives against the fungal pathogens Histoplasma capsulatum and Cryptococcus neoformans

Invasive fungal disease constitutes a growing health burden and development of novel antifungal drugs with high potency and selectivity against new fungal molecular targets are urgently needed. Previously, an aminothiazole derivative, designated as 41F5, was identified in our laboratories as highly...

詳細記述

保存先:
書誌詳細
出版年:Bioorg Med Chem
主要な著者: Khalil, Ahmed, Edwards, Jessica A., Rappleye, Chad A., Tjarks, Werner
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4302056/
https://ncbi.nlm.nih.gov/pubmed/25543205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2014.12.006
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