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Design, synthesis, and biological evaluation of aminothiazole derivatives against the fungal pathogens Histoplasma capsulatum and Cryptococcus neoformans

Invasive fungal disease constitutes a growing health burden and development of novel antifungal drugs with high potency and selectivity against new fungal molecular targets are urgently needed. Previously, an aminothiazole derivative, designated as 41F5, was identified in our laboratories as highly...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Bioorg Med Chem
Päätekijät: Khalil, Ahmed, Edwards, Jessica A., Rappleye, Chad A., Tjarks, Werner
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4302056/
https://ncbi.nlm.nih.gov/pubmed/25543205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2014.12.006
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