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Ca(2+) Sparks and Ca(2+) Waves are the subcellular events underlying Ca(2+) overload during ischemia and reperfusion in perfused intact hearts
Abnormal intracellular Ca(2+) cycling plays a key role in cardiac dysfunction, particularly during the setting of ischemia/reperfusion (I/R). During ischemia there is an increase in cytosolic and sarcoplasmic reticulum (SR) Ca(2+). At the onset of reperfusion there is a transient and abrupt increase...
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| Publicado no: | J Mol Cell Cardiol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4302011/ https://ncbi.nlm.nih.gov/pubmed/25451173 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2014.10.011 |
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