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Ischemic preconditioning and diazoxide limit mitochondrial Ca(2+) overload during ischemia/reperfusion: Role of reactive oxygen species

BACKGROUND: Generation of reactive oxygen species (ROS) is associated with cardioprotection imparted by ischemic preconditioning (IPC) and pharmacological PC (PPC). The authors have previously shown that IPC or PPC, using the mitochondrial ATP-sensitive K(+) channel opener diazoxide (DZ), reduce mit...

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Detalhes bibliográficos
Main Authors: Eaton, Matt, Hernandez, Lisa A, Schaefer, Saul
Formato: Artigo
Idioma:Inglês
Publicado em: Pulsus Group Inc 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2716229/
https://ncbi.nlm.nih.gov/pubmed/19641667
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