Ischemic preconditioning and diazoxide limit mitochondrial Ca(2+) overload during ischemia/reperfusion: Role of reactive oxygen species

BACKGROUND: Generation of reactive oxygen species (ROS) is associated with cardioprotection imparted by ischemic preconditioning (IPC) and pharmacological PC (PPC). The authors have previously shown that IPC or PPC, using the mitochondrial ATP-sensitive K(+) channel opener diazoxide (DZ), reduce mit...

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Dades bibliogràfiques
Autors principals: Eaton, Matt, Hernandez, Lisa A, Schaefer, Saul
Format: Artigo
Idioma:Inglês
Publicat: Pulsus Group Inc 2005
Matèries:
Experimental Cardiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2716229/
https://ncbi.nlm.nih.gov/pubmed/19641667
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