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Pavarotti/MKLP1 regulates microtubule sliding and neurite outgrowth in Drosophila neurons

Recently, we demonstrated that kinesin-1 can slide microtubules against each other providing the mechanical force required for initial neurite extension in Drosophila neurons. This sliding is only observed in young neurons actively forming neurites and is dramatically downregulated in older neurons....

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發表在:Curr Biol
Main Authors: del Castillo, Urko, Lu, Wen, Winding, Michael, Lakonishok, Margot, Gelfand, Vladimir I.
格式: Artigo
語言:Inglês
出版: 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4302008/
https://ncbi.nlm.nih.gov/pubmed/25557664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2014.11.008
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