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Interplay between kinesin-1 and cortical dynein during axonal outgrowth and microtubule organization in Drosophila neurons

In this study, we investigated how microtubule motors organize microtubules in Drosophila neurons. We showed that, during the initial stages of axon outgrowth, microtubules display mixed polarity and minus-end-out microtubules push the tip of the axon, consistent with kinesin-1 driving outgrowth by...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: del Castillo, Urko, Winding, Michael, Lu, Wen, Gelfand, Vladimir I
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4739764/
https://ncbi.nlm.nih.gov/pubmed/26615019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.10140
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