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Interplay between kinesin-1 and cortical dynein during axonal outgrowth and microtubule organization in Drosophila neurons

In this study, we investigated how microtubule motors organize microtubules in Drosophila neurons. We showed that, during the initial stages of axon outgrowth, microtubules display mixed polarity and minus-end-out microtubules push the tip of the axon, consistent with kinesin-1 driving outgrowth by...

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Библиографические подробности
Опубликовано в: :eLife
Главные авторы: del Castillo, Urko, Winding, Michael, Lu, Wen, Gelfand, Vladimir I
Формат: Artigo
Язык:Inglês
Опубликовано: eLife Sciences Publications, Ltd 2015
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4739764/
https://ncbi.nlm.nih.gov/pubmed/26615019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.10140
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