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Pavarotti/MKLP1 regulates microtubule sliding and neurite outgrowth in Drosophila neurons

Recently, we demonstrated that kinesin-1 can slide microtubules against each other providing the mechanical force required for initial neurite extension in Drosophila neurons. This sliding is only observed in young neurons actively forming neurites and is dramatically downregulated in older neurons....

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Publicado en:Curr Biol
Autores principales: del Castillo, Urko, Lu, Wen, Winding, Michael, Lakonishok, Margot, Gelfand, Vladimir I.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4302008/
https://ncbi.nlm.nih.gov/pubmed/25557664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2014.11.008
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