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Promoter Occupancy of STAT1 in Interferon Responses Is Regulated by Processive Transcription

Interferons regulate immunity by inducing DNA binding of the transcription factor STAT1 through Y701 phosphorylation. Transcription by STAT1 needs to be restricted to minimize the adverse effects of prolonged immune responses. It remains unclear how STAT1 inactivation is regulated such that the tran...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Wiesauer, Ivana, Gaumannmüller, Clemens, Steinparzer, Iris, Strobl, Birgit, Kovarik, Pavel
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4301719/
https://ncbi.nlm.nih.gov/pubmed/25512607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01097-14
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