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Promoter Occupancy of STAT1 in Interferon Responses Is Regulated by Processive Transcription
Interferons regulate immunity by inducing DNA binding of the transcription factor STAT1 through Y701 phosphorylation. Transcription by STAT1 needs to be restricted to minimize the adverse effects of prolonged immune responses. It remains unclear how STAT1 inactivation is regulated such that the tran...
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| Udgivet i: | Mol Cell Biol |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4301719/ https://ncbi.nlm.nih.gov/pubmed/25512607 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01097-14 |
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