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Structure of Acidic pH Dengue Virus Showing the Fusogenic Glycoprotein Trimers
Flaviviruses undergo large conformational changes during their life cycle. Under acidic pH conditions, the mature virus forms transient fusogenic trimers of E glycoproteins that engage the lipid membrane in host cells to initiate viral fusion and nucleocapsid penetration into the cytoplasm. However,...
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| Foilsithe in: | J Virol |
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| Main Authors: | , , , , , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
American Society for Microbiology
2014
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4301137/ https://ncbi.nlm.nih.gov/pubmed/25355881 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02411-14 |
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