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Structure of Acidic pH Dengue Virus Showing the Fusogenic Glycoprotein Trimers
Flaviviruses undergo large conformational changes during their life cycle. Under acidic pH conditions, the mature virus forms transient fusogenic trimers of E glycoproteins that engage the lipid membrane in host cells to initiate viral fusion and nucleocapsid penetration into the cytoplasm. However,...
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| Publicado no: | J Virol |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4301137/ https://ncbi.nlm.nih.gov/pubmed/25355881 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02411-14 |
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