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Dengue structure differs at the temperatures of its human and mosquito hosts

We report on a conformational transition of dengue virus when changing the temperature from that present in its mosquito vectors to that of its human host. Using cryoelectron microscopy, we show that although the virus has a smooth surface, a diameter of ∼500 Å, and little exposed membrane at room t...

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Hlavní autoři: Zhang, Xinzheng, Sheng, Ju, Plevka, Pavel, Kuhn, Richard J., Diamond, Michael S., Rossmann, Michael G.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3637732/
https://ncbi.nlm.nih.gov/pubmed/23569243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1304300110
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