Clonal Evolution of CD8(+) T Cell Responses against Latent Viruses: Relationship among Phenotype, Localization, and Function

Human cytomegalovirus (hCMV) infection is characterized by a vast expansion of resting effector-type virus-specific T cells in the circulation. In mice, interleukin-7 receptor α (IL-7Rα)-expressing cells contain the precursors for long-lived antigen-experienced CD8(+) T cells, but it is unclear if s...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Remmerswaal, Ester B. M., Klarenbeek, Paul L., Alves, Nuno L., Doorenspleet, Marieke E., van Schaik, Barbera D. C., Esveldt, Rebecca E. E., Idu, Mirza M., van Leeuwen, Ester M. M., van der Bom-Baylon, Nelly, van Kampen, Antoine H. C., Koch, Sven D., Pircher, Hanspeter, Bemelman, Frederike J., ten Brinke, Anja, Baas, Frank, ten Berge, Ineke J. M., van Lier, Rene A.W., de Vries, Niek
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Cellular Response to Infection
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4301136/
https://ncbi.nlm.nih.gov/pubmed/25339770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02003-14
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