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Molecular and evolutionary insights into the structural organization of cation chloride cotransporters
Cation chloride cotransporters (CCC) play an essential role for neuronal chloride homeostasis. K(+)-Cl(−) cotransporter (KCC2), is the principal Cl(−)-extruder, whereas Na(+)-K(+)-Cl(−) cotransporter (NKCC1), is the major Cl(−)-uptake mechanism in many neurons. As a consequence, the action of the in...
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| Publicado no: | Front Cell Neurosci |
|---|---|
| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4301019/ https://ncbi.nlm.nih.gov/pubmed/25653592 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2014.00470 |
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