A Lethal Murine Infection Model for Dengue Virus 3 in AG129 Mice Deficient in Type I and II Interferon Receptors Leads to Systemic Disease

The mosquito-borne disease dengue (DEN) is caused by four serologically and genetically related viruses, termed DENV-1 to DENV-4. Infection with one DENV usually leads to acute illness and results in lifelong homotypic immunity, but individuals remain susceptible to infection by the other three DENV...

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Publicado en:J Virol
Autores principales: Sarathy, Vanessa V., White, Mellodee, Li, Li, Gorder, Summer R., Pyles, Richard B., Campbell, Gerald A., Milligan, Gregg N., Bourne, Nigel, Barrett, Alan D. T.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2014
Materias:
Pathogenesis and Immunity
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4300670/
https://ncbi.nlm.nih.gov/pubmed/25392217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01320-14
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