Characterization of lethal dengue virus type 4 (DENV-4) TVP-376 infection in mice lacking both IFN-α/β and IFN-γ receptors (AG129) and comparison with the DENV-2 AG129 mouse model

Dengue is a mosquito-borne disease caused by four related but distinct dengue viruses, DENV-1 to DENV-4. Dengue is endemic in most tropical countries, and over a third of the world's population is at risk of being infected. Although the global burden is high, no vaccine or antiviral is licensed...

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Publicat a:J Gen Virol
Autors principals: Sarathy, Vanessa V., Infante, Ernesto, Li, Li, Campbell, Gerald A., Wang, Tian, Paessler, Slobodan, Robert Beatty, P., Harris, Eva, Milligan, Gregg N., Bourne, Nigel, Barrett, Alan D. T.
Format: Artigo
Idioma:Inglês
Publicat: Microbiology Society 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4635480/
https://ncbi.nlm.nih.gov/pubmed/26296350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/jgv.0.000246
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