Virological and Immunological Characterization of Novel NYVAC-Based HIV/AIDS Vaccine Candidates Expressing Clade C Trimeric Soluble gp140(ZM96) and Gag(ZM96)-Pol-Nef(CN54) as Virus-Like Particles

The generation of vaccines against HIV/AIDS able to induce long-lasting protective immunity remains a major goal in the HIV field. The modest efficacy (31.2%) against HIV infection observed in the RV144 phase III clinical trial highlighted the need for further improvement of HIV vaccine candidates,...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Perdiguero, Beatriz, Gómez, Carmen Elena, Cepeda, Victoria, Sánchez-Sampedro, Lucas, García-Arriaza, Juan, Mejías-Pérez, Ernesto, Jiménez, Victoria, Sánchez, Cristina, Sorzano, Carlos Óscar S., Oliveros, Juan Carlos, Delaloye, Julie, Roger, Thierry, Calandra, Thierry, Asbach, Benedikt, Wagner, Ralf, Kibler, Karen V., Jacobs, Bertram L., Pantaleo, Giuseppe, Esteban, Mariano
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4300665/
https://ncbi.nlm.nih.gov/pubmed/25355891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02469-14
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