JC Virus Quasispecies Analysis Reveals a Complex Viral Population Underlying Progressive Multifocal Leukoencephalopathy and Supports Viral Dissemination via the Hematogenous Route

Opportunistic infection of oligodendrocytes by human JC polyomavirus may result in the development of progressive multifocal encephalopathy in immunocompromised individuals. Neurotropic JC virus generally harbors reorganized noncoding control region (NCCR) DNA interspersed on the viral genome betwee...

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Van Loy, Tom, Thys, Kim, Ryschkewitsch, Caroline, Lagatie, Ole, Monaco, Maria C., Major, Eugene O., Tritsmans, Luc, Stuyver, Lieven J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2014
Schlagworte:
Genome Replication and Regulation of Viral Gene Expression
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4300648/
https://ncbi.nlm.nih.gov/pubmed/25392214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02565-14
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