JC Virus Quasispecies Analysis Reveals a Complex Viral Population Underlying Progressive Multifocal Leukoencephalopathy and Supports Viral Dissemination via the Hematogenous Route

Opportunistic infection of oligodendrocytes by human JC polyomavirus may result in the development of progressive multifocal encephalopathy in immunocompromised individuals. Neurotropic JC virus generally harbors reorganized noncoding control region (NCCR) DNA interspersed on the viral genome betwee...

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Publicat a:J Virol
Autors principals: Van Loy, Tom, Thys, Kim, Ryschkewitsch, Caroline, Lagatie, Ole, Monaco, Maria C., Major, Eugene O., Tritsmans, Luc, Stuyver, Lieven J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2014
Matèries:
Genome Replication and Regulation of Viral Gene Expression
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4300648/
https://ncbi.nlm.nih.gov/pubmed/25392214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02565-14
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