JC Virus Quasispecies Analysis Reveals a Complex Viral Population Underlying Progressive Multifocal Leukoencephalopathy and Supports Viral Dissemination via the Hematogenous Route

Opportunistic infection of oligodendrocytes by human JC polyomavirus may result in the development of progressive multifocal encephalopathy in immunocompromised individuals. Neurotropic JC virus generally harbors reorganized noncoding control region (NCCR) DNA interspersed on the viral genome betwee...

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Библиографические подробности
Опубликовано в: :J Virol
Главные авторы: Van Loy, Tom, Thys, Kim, Ryschkewitsch, Caroline, Lagatie, Ole, Monaco, Maria C., Major, Eugene O., Tritsmans, Luc, Stuyver, Lieven J.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2014
Предметы:
Genome Replication and Regulation of Viral Gene Expression
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4300648/
https://ncbi.nlm.nih.gov/pubmed/25392214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02565-14
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