TNFR1-JNK signaling is the shared pathway of neuroinflammation and neurovascular damage after LPS-sensitized hypoxic-ischemic injury in the immature brain

BACKGROUND: Hypoxic-ischemia (HI) and inflammation are the two major pathogenic mechanisms of brain injury in very preterm infants. The neurovascular unit is the major target of HI injury in the immature brain. Systemic inflammation may worsen HI by up-regulating neuroinflammation and disrupting the...

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Publicado no:J Neuroinflammation
Main Authors: Wang, Lan-Wan, Chang, Ying-Chao, Chen, Shyi-Jou, Tseng, Chien-Hang, Tu, Yi-Fang, Liao, Nan-Shih, Huang, Chao-Ching, Ho, Chien-Jung
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4300587/
https://ncbi.nlm.nih.gov/pubmed/25540015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-014-0215-2
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