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JNK signaling is the shared pathway linking neuroinflammation, blood–brain barrier disruption, and oligodendroglial apoptosis in the white matter injury of the immature brain

BACKGROUND: White matter injury is the major form of brain damage in very preterm infants. Selective white matter injury in the immature brain can be induced by lipopolysaccharide (LPS)-sensitized hypoxic-ischemia (HI) in the postpartum (P) day 2 rat pups whose brain maturation status is equivalent...

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Detalhes bibliográficos
Main Authors: Wang, Lan-Wan, Tu, Yi-Fang, Huang, Chao-Ching, Ho, Chien-Jung
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3414763/
https://ncbi.nlm.nih.gov/pubmed/22805152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-9-175
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