IL-6 Receptor α Defines Effector Memory CD8(+) T Cells Producing Th2 Cytokines and Expanding in Asthma

Rationale: Cytokine receptors can be markers defining different T-cell subsets and considered as therapeutic targets. The association of IL-6 and IL-6 receptor α (IL-6Rα) with asthma was reported, suggesting their involvement in asthma. Objectives: To determine whether and how IL-6Rα defines a disti...

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Vydáno v:Am J Respir Crit Care Med
Hlavní autoři: Lee, Naeun, You, Sungyong, Shin, Min Sun, Lee, Won-Woo, Kang, Ki Soo, Kim, Sang Hyun, Kim, Wan-Uk, Homer, Robert J., Kang, Min-Jong, Montgomery, Ruth R., Dela Cruz, Charles S., Shaw, Albert C., Lee, Patty J., Chupp, Geoffrey L., Hwang, Daehee, Kang, Insoo
Médium: Artigo
Jazyk:Inglês
Vydáno: American Thoracic Society 2014
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4299645/
https://ncbi.nlm.nih.gov/pubmed/25390970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201403-0601OC
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