IL-7 receptor alpha defines heterogeneity and signature of human effector memory CD8(+) T cells in high dimensional analysis

The IL-7 receptor alpha chain (IL-7Rα or CD127) can be differentially expressed in memory CD8(+) T cells. Here we investigated whether IL-7Rα could serve as a key molecule in defining a comprehensive landscape of heterogeneity in human effector memory (EM) CD8(+) T cells using high-dimensional Cytom...

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Veröffentlicht in:Cell Immunol
Hauptverfasser: Shin, Min Sun, Kim, Dongjoo, Yim, Kristina, Park, Hong-Jai, You, Sungyong, Dong, Xuemei, Koumpouras, Fotios, Shaw, Albert C., Fan, Rong, Krishnaswamy, Smita, Kang, Insoo
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7415611/
https://ncbi.nlm.nih.gov/pubmed/32619811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2020.104155
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