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Baclofen and Other GABA(B) Receptor Agents Are Allosteric Modulators of the CXCL12 Chemokine Receptor CXCR4

CXCR4, a receptor for the chemokine CXCL12 (stromal-cell derived factor-1α), is a G-protein-coupled receptor (GPCR), expressed in the immune and CNS and integrally involved in various neurological disorders. The GABA(B) receptor is also a GPCR that mediates metabotropic action of the inhibitory neur...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Guyon, Alice, Kussrow, Amanda, Olmsted, Ian Roys, Sandoz, Guillaume, Bornhop, Darryl J., Nahon, Jean-Louis
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4299549/
https://ncbi.nlm.nih.gov/pubmed/23843532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.6070-11.2013
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