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Functional analysis of myosin missense mutations in familial hypertrophic cardiomyopathy.

To analyze potential functional consequences of myosin heavy chain (MHC) mutations identified in patients with familial hypertrophic cardiomyopathy (FHC), we have assessed the stability of the mutant MHCs and their ability to form thick filaments. Constructs encoding wild-type rat alpha MHC and seve...

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Bibliografiske detaljer
Main Authors: Straceski, A J, Geisterfer-Lowrance, A, Seidman, C E, Seidman, J G, Leinwand, L A
Format: Artigo
Sprog:Inglês
Udgivet: 1994
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC42994/
https://ncbi.nlm.nih.gov/pubmed/8290568
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