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Function of the Outer Membrane of Escherichia coli as a Permeability Barrier to Beta-Lactam Antibiotics

On the basis of a simple theoretical model, the ease of penetration of β-lactam antibiotics through the outer membrane of Escherichia coli was measured. The cell envelope was found to act as a diffusion barrier to both penicillins and cephalosporins. The validity of the model and the cooperative act...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Zimmermann, Willy, Rosselet, Armel
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1977
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC429920/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/334063/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.12.3.368
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