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Penetration of the outer membrane of Pseudomonas aeruginosa by synergistic combinations of beta-lactam and aminoglycoside antibiotics.

The mechanism of the synergistic action of carbenicillin-gentamicin and moxalactam-tobramycin combinations against Pseudomonas aeruginosa ATCC 9027 was investigated. Disruption of the outer membrane penetration barrier by EDTA treatment enhanced the activity of both combinations against the cells du...

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Pubblicato in:Antimicrob Agents Chemother
Autori principali: Scudamore, R A, Goldner, M
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 1982
Soggetti:
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC182063/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6810756/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.21.6.1007
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