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Function of the Outer Membrane of Escherichia coli as a Permeability Barrier to Beta-Lactam Antibiotics
On the basis of a simple theoretical model, the ease of penetration of β-lactam antibiotics through the outer membrane of Escherichia coli was measured. The cell envelope was found to act as a diffusion barrier to both penicillins and cephalosporins. The validity of the model and the cooperative act...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1977
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC429920/ https://ncbi.nlm.nih.gov/pubmed/334063 |
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