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MicroRNA-519a is a novel oncomir conferring tamoxifen resistance by targeting a network of tumour-suppressor genes in ER+ breast cancer

Tamoxifen is an endocrine therapy which is administered to up to 70% of all breast cancer patients with oestrogen receptor alpha (ERα) expression. Despite the initial response, most patients eventually acquire resistance to the drug. MicroRNAs (miRNAs) are a class of small non-coding RNAs which have...

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Bibliografische gegevens
Gepubliceerd in:J Pathol
Hoofdauteurs: Ward, Aoife, Shukla, Kirti, Balwierz, Aleksandra, Soons, Zita, König, Rainer, Sahin, Özgür, Wiemann, Stefan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley & Sons, Ltd. 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4298809/
https://ncbi.nlm.nih.gov/pubmed/24752803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4363
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