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MicroRNA-519a is a novel oncomir conferring tamoxifen resistance by targeting a network of tumour-suppressor genes in ER+ breast cancer
Tamoxifen is an endocrine therapy which is administered to up to 70% of all breast cancer patients with oestrogen receptor alpha (ERα) expression. Despite the initial response, most patients eventually acquire resistance to the drug. MicroRNAs (miRNAs) are a class of small non-coding RNAs which have...
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出版年: | J Pathol |
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主要な著者: | , , , , , , |
フォーマット: | Artigo |
言語: | Inglês |
出版事項: |
John Wiley & Sons, Ltd.
2014
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4298809/ https://ncbi.nlm.nih.gov/pubmed/24752803 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4363 |
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