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EGFR signaling promotes self-renewal through the establishment of cell polarity in Drosophila follicle stem cells

Epithelial stem cells divide asymmetrically, such that one daughter replenishes the stem cell pool and the other differentiates. We found that, in the epithelial follicle stem cell (FSC) lineage of the Drosophila ovary, epidermal growth factor receptor (EGFR) signaling functions specifically in the...

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Podrobná bibliografie
Vydáno v:eLife
Hlavní autoři: Castanieto, Angela, Johnston, Michael J, Nystul, Todd G
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4298699/
https://ncbi.nlm.nih.gov/pubmed/25437306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.04437
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