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EGFR signaling promotes self-renewal through the establishment of cell polarity in Drosophila follicle stem cells

Epithelial stem cells divide asymmetrically, such that one daughter replenishes the stem cell pool and the other differentiates. We found that, in the epithelial follicle stem cell (FSC) lineage of the Drosophila ovary, epidermal growth factor receptor (EGFR) signaling functions specifically in the...

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Publicado en:eLife
Autores principales: Castanieto, Angela, Johnston, Michael J, Nystul, Todd G
Formato: Artigo
Lenguaje:Inglês
Publicado: eLife Sciences Publications, Ltd 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4298699/
https://ncbi.nlm.nih.gov/pubmed/25437306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.04437
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