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EGFR signaling promotes self-renewal through the establishment of cell polarity in Drosophila follicle stem cells

Epithelial stem cells divide asymmetrically, such that one daughter replenishes the stem cell pool and the other differentiates. We found that, in the epithelial follicle stem cell (FSC) lineage of the Drosophila ovary, epidermal growth factor receptor (EGFR) signaling functions specifically in the...

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Détails bibliographiques
Publié dans:eLife
Auteurs principaux: Castanieto, Angela, Johnston, Michael J, Nystul, Todd G
Format: Artigo
Langue:Inglês
Publié: eLife Sciences Publications, Ltd 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4298699/
https://ncbi.nlm.nih.gov/pubmed/25437306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.04437
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