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EGFR signaling promotes self-renewal through the establishment of cell polarity in Drosophila follicle stem cells

Epithelial stem cells divide asymmetrically, such that one daughter replenishes the stem cell pool and the other differentiates. We found that, in the epithelial follicle stem cell (FSC) lineage of the Drosophila ovary, epidermal growth factor receptor (EGFR) signaling functions specifically in the...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Castanieto, Angela, Johnston, Michael J, Nystul, Todd G
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4298699/
https://ncbi.nlm.nih.gov/pubmed/25437306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.04437
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