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Leptin Modulates the Intrinsic Excitability of AgRP/NPY Neurons in the Arcuate Nucleus of the Hypothalamus

The hypothalamic arcuate nucleus (ARH) is a brain region critical for regulation of food intake and a primary area for the action of leptin in the CNS. In lean mice, the adipokine leptin inhibits neuropeptide Y (NPY) and agouti-related peptide (AgRP) neuronal activity, resulting in decreased food in...

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Bibliografske podrobnosti
izdano v:J Neurosci
Main Authors: Baver, Scott B., Hope, Kevin, Guyot, Shannon, Bjørbaek, Christian, Kaczorowski, Catherine, O'Connell, Kristen M. S.
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4298648/
https://ncbi.nlm.nih.gov/pubmed/24741039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4861-12.2014
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