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A critical period for the trophic actions of leptin on AgRP neurons in the arcuate nucleus of the hypothalamus
In the developing hypothalamus, the fat-derived hormone leptin stimulates the growth of axons from the arcuate nucleus of the hypothalamus (ARH) to other regions that control energy balance. These projections are significantly reduced in leptin deficient (Lep(ob/ob)) mice and this phenotype is large...
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| Veröffentlicht in: | J Comp Neurol |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6040218/ https://ncbi.nlm.nih.gov/pubmed/28891045 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cne.24327 |
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