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Ectopic Expression of Fas Ligand on Cardiomyocytes Renders Cardiac Allografts Resistant to CD4(+) T-cell Mediated Rejection
Fas Ligand limits inflammatory injury and permits allograft survival by inducing apoptosis of Fas-bearing lymphocytes. Previous studies have shown that the CD4(+) T-cell is both sufficient and required for murine cardiac allograft rejection. Here, utilizing a transgenic mouse that over-expresses Fas...
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| Gepubliceerd in: | Cell Immunol |
|---|---|
| Hoofdauteurs: | , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2014
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4298462/ https://ncbi.nlm.nih.gov/pubmed/25497973 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2014.11.007 |
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